October 2, 2020, President Donald Trump introduced he and First Woman Melania Trump had examined optimistic for SARS-CoV-2. Each reported having gentle signs. Based on a report1 by Science Journal, the President was transferred to Walter Reed Nationwide Army Medical Heart in Bethesda, Maryland, that very same day. His signs included fever, fatigue and congestion.
Based on his docs, he additionally skilled a short lived drop in oxygen saturation stage, from the conventional 98% to 93%, and was given supplemental oxygen earlier than being transported to Walter Reed.2 As a basic guideline, medical care is beneficial in case your oxygen saturation is under 94%.3
Melania Trump opted to relaxation and self-isolate within the White Home.4 Her signs, which had been reportedly milder than the president’s, included gentle cough and headache. No information has emerged concerning her course of therapy.
The Two Phases of Illness Require Totally different Remedies
Based on stories, President Trump has been given quite a lot of remedies, together with each holistic alternate options and experimental medication, prompting some well being professionals to query why they’re “throwing the kitchen sink at him.” Whereas aggressive and early therapy is strongly beneficial, sure treatments are greatest used at particular occasions in the course of the illness course of.
As detailed in “COVID-19 Critical Care,” the Entrance-Line COVID-19 Crucial Care (FLCCC) Alliance5 has recognized two distinct but overlapping phases of the illness, and timing of the therapy for every is essential. The primary section is the viral replication stage.
Peak viral replication takes place on the earliest indicators of signs, which embody chilly/flu-like signs, lack of style and scent, myalgia (muscle ache) and basic malaise. At the moment, the main focus ought to be on antiviral therapies. Anti-inflammatories (which is what steroids are) ought to be prevented, as you do not need to dampen your immune system at this stage.
In the course of the second section, hyperinflammatory immune responses turn out to be obvious. At this stage, the FLCCC’s MATH+ protocol, which has been delivered to the White Home on a minimum of 4 events, requires the administration of intravenous (IV) methylprednisolone (a steroid) to suppress the immune system and dampen cytokine storm, IV ascorbic acid (vitamin C) and subcutaneous heparin to forestall blood clots.
Collectively, this method addresses the three core pathological processes seen in COVID-19, specifically hyperinflammation, hypercoagulability of the blood, and hypoxia (shortness of breath on account of low oxygenation). The graphic under particulars the 2 phases of illness, and the FLCCC’s steered therapy focus for every.
President’s Remedy Protocol
The President’s therapy protocol has reportedly included the next.6,7,8,9,10 As you possibly can see, whereas there are specific similarities to the MATH+ protocol, there are additionally distinct variations:
Remdesivir is an experimental antiviral drug from Gilead Sciences that has been granted emergency authorization by the U.S. Meals and Drug Administration. The IV drug, which is meant for use for late-stage extreme COVID-19 an infection, has been proven to trigger extreme uncomfortable side effects in 60% of sufferers, and would not scale back the demise price. It merely reduces the restoration price by a mean of 31%, or 4 days.11
REGN-COV2 is an experimental monoclonal antibody cocktail made by Regeneron that has been described12 as “genetically engineered plasma” and a “passive vaccine.” The president apparently obtained an 8-gram infusion, which is a significantly bigger dose than the two.4-gram dose proven to scale back SARS-CoV-2 ranges.
Based on George Yancopoulos, co-founder and chief scientific officer of Regeneron, maker of REGN-COV2, the bigger dose was doubtless given out of “an abundance of warning,” as the corporate’s knowledge suggests larger doses could also be more practical in decreasing the viral load and will present longer lasting results whereas having “very, very restricted danger.”13
Dexamethasone, a steroid used to forestall immune system overreaction. Some docs query14 the usage of this drug, because it’s sometimes been reserved for sufferers with late stage illness. However, the FLCCC has famous that dexamethasone is a much less efficient choice than the methylprednisolone beneficial within the MATH+ protocol.15
Zinc — As defined in “Swiss Protocol for COVID — Quercetin and Zinc” and “Zinc Is Key to HCQ Protocol,” zinc performs a vital position in immunity and blood clotting, and successfully inhibits viral replication. Sadly, zinc is poorly absorbed, which seems to be why protocols utilizing it along with zinc ionophores corresponding to quercetin or hydroxychloroquine, which usher zinc into your cells, are so efficient.
Famotidine (model title Pepcid), an antacid drug included as an non-compulsory addition within the MATH+ protocol,16 has antiviral properties and stimulates the immune cells of your innate and adaptive immune system. In a single COVID-19 examine, famotidine given inside 24 hours of hospital admission was discovered to scale back the chance for demise and intubation.17
Melatonin — As detailed in “Melatonin for Sepsis,” melatonin performs an essential position in your immune operate, has antioxidant and mitochondrial-protective capabilities, and has been proven to be efficient towards numerous bacterial and viral infections.
It is also been proven to reverse septic shock signs by reducing synthesis of proinflammatory cytokines and stopping oxidative injury, endotoxemia and metabolic alterations. The potential position of melatonin in COVID-19 an infection has been addressed in an in depth and totally referenced March 14, 2020, article by medical researcher Doris Loh, printed within the Italian on-line journal Evolutamente.18
Is the President Being Overtreated?
As talked about, some well being practitioners have questioned whether or not the President may be receiving extreme care. Using the steroid dexamethasone, which might sometimes be reserved for extreme instances, seems to rattle critics essentially the most. Few if any have introduced up the mediocre trial outcomes of remdesivir, or the truth that this drug can also be for late-stage illness.
Based on the FLCCC, COVID-19 is a steroid-responsive illness, and steroids are a key part of Section 2 therapy. That mentioned, it could be true that Walter Reed docs jumped the gun in prescribing these medication if, certainly, the president solely had gentle signs. Alternatively, maybe the president’s sickness was extra extreme than has been reported.
Whereas I do not need to speculate an excessive amount of about these prospects at this level, I’ll merely word that in response to the FLCCC, your oxygen saturation is a key indicator of pulmonary involvement. As soon as your oxygen saturation begins to say no, you might be coming into the early pulmonary section the place irritation is quickly growing. So, it is attainable that the president’s dip in oxygen saturation is what prompted the usage of an anti-inflammatory steroid (dexamethasone).
The president additionally has a number of the comorbidities or danger elements identified to put him at elevated danger for extra extreme illness, primarily age (he is 74), extra weight and gentle or average hypertension (though it is mentioned to be beneath management). He clearly suffers from insulin resistance primarily based on his weight, hypertension and consuming habits.
The president’s doctor, Navy Commander Dr. Sean Conley who, like me, is a D.O. or osteopathic doctor, advised reporters throughout an October 3, 2020, press convention that his workforce was utilizing a “multiprong” method to deal with the president. He additionally talked about President Trump had requested about hydroxychloroquine, however that he had not been given the drug for unspecified causes. Based on Conley:19
“[President Trump] is receiving all the customary of care and past for routine, worldwide COVID protocols. He is the president. I did not need to maintain something again. If there was any chance that it could add worth to his care and expedite his return, I wished to take it.”
Sadly, however not surprisingly, regardless of the now overwhelming evidence supporting the use of vitamin D, most media have reverted again to pushing the concept vitamin D is ineffective. However, the president’s therapy protocol does present a touch that different remedies corresponding to the usage of vitamin D, zinc and melatonin are gaining inroads in scientific follow.
The MATH+ Protocol
As talked about, President Trump’s therapy protocol contains a number of the treatments specified within the FLCCC’s MATH+ protocol, however not all. His therapy additionally seems to have been extra aggressive than sometimes prescribed, with the early administration of each a steroid and remdesivir.
It is considerably disappointing to see the complete MATH+ protocol was not adopted, contemplating the FLCCC has shared the protocol with the White Home on a number of events. In a brief essay20 co-written by your complete FLCCC workforce, they categorical their conviction that the MATH+ protocol is likely one of the greatest, simplest, vital care protocols for COVID-19 to this point.
The newest model of the MATH+ protocol, which was briefly summarized above, is detailed in “Quercetin and Vitamin C: Synergistic Therapy for COVID-19.” Because the headline reveals, that article additionally opinions a number of the newest analysis supporting the usage of quercetin, which acts in an analogous method as hydroxychloroquine.
Nebulized Hydrogen Peroxide — A Extremely Efficient Residence Treatment
For my part, the President’s medical workforce missed (and doubtless weren’t even conscious of) some of the efficient therapy choices, specifically nebulized hydrogen peroxide. It is a house treatment I like to recommend everybody familiarize themselves with, as in lots of instances it might probably enhance signs inside mere hours. It’s notably efficient in those that are within the later phases of the sickness.
Dr. David Brownstein, who has efficiently handled over 100 COVID-19 sufferers with nebulized hydrogen peroxide, printed a case paper21 about this therapy within the July 2020 subject of Science, Public Well being Coverage and The Legislation. He additionally discusses its advantages in a recent interview I did with him.
In my April 2020 article, “Could Hydrogen Peroxide Treat Coronavirus?” I reviewed a number of the fundamental science of how hydrogen peroxide works, in addition to a number of the research assessing its therapeutic potential. Essentially the most related examine22 was printed in March 2020 within the Journal of Hospital An infection. They studied 0.5% hydrogen peroxide, and located it killed human coronaviruses, together with the coronaviruses accountable for SARS and MERS.
Nebulized hydrogen peroxide is extraordinarily secure. Brownstein has used it for 25 years with no unwell results being discovered. It is also extremely cheap, and you may administer it at house, with no prescription. For my part, it is likely one of the very best therapies for viral infections like SARS-CoV-2 and even worse respiratory viruses that can doubtless be unleashed sooner or later.
I strongly advocate shopping for a desktop nebulizer. It wants to provide a really high-quality mist, and desktop variations are stronger than handheld battery operated fashions. The one I exploit is the Pari Trek S Compressor Aerosol System with a face masks, (bought individually) not with the equipped mouth piece.
You will need to purchase the tools and peroxide BEFORE you want it, as the earlier you deal with the an infection the higher your outcomes will probably be, though the testimonials are unbelievably spectacular even in late stage sickness. It’s not essential to deal with your self preventively, however solely in case you are sick or uncovered to somebody who’s.
Whereas I have been utilizing a 0.1% dilution, Brownstein makes use of an excellent decrease focus of simply 0.04%. Neither Brownstein nor I like to recommend utilizing business 3% hydrogen peroxide present in most grocery shops, because it has doubtlessly poisonous chemical stabilizers in it. For optimum advantages, use food-grade peroxide and dilute it appropriately, utilizing saline.
To dilute 35% food-grade peroxide right into a 0.04% resolution, first dilute it down to three% by mixing 1 half peroxide with 10 elements sterile water, then take 3 cubic centimeters (CCs) of that 3% dilution and add it to a 250CC bag of regular saline. This brings it right down to a .04% hydrogen peroxide focus. Within the video above, I’m going over the fundamentals of easy methods to do nebulized peroxide.